Ozone Therapy for Cancer


It is important to note that ozone therapy should not be used in place of any traditional cancer therapies and treatments.

If you have been diagnosed with cancer, please seek the medical advice of your doctor.

The author of this article does not make any medical claims; please consult your doctor for any final medical decision. 

In addition, please conduct your research.

Ozone therapy should be used ONLY as an adjuvant modality alongside traditional cancer treatment.

Over several decades, multiple journals have published positive studies on the capacity of ozone to induce direct damage to tumour cells and, as well, to enhance the effects of radiotherapy and chemotherapy.

For the past sixty years, the robust journal Nature has been publishing articles on the effects of ozone and ionising radiation.

  • In an article written in 1958, the author described how ozone has a similar effect on humans to that of radiation.
  • This framework was drawn from the fact that ozone and ionising radiation both involved the generation of reactive oxygen species (ROS), which induce oxidative stress on the human body, leading to their effects being palliated by antioxidants.

Furthermore, in another prestigious journal, Science, the report described how ozone could selectively inhibit the growth of different human tumour cells without affecting non-tumour cell lines.

Additionally, ozone has been shown to directly damage the cell membrane by oxidising the fatty acids that compose it.

This is an integral point to consider when discussing ozone’s anti-cancer mechanisms.

  • Cancer cells already have an overloaded antioxidant system because of the increased ROS levels.
  • So, when ozone is systemically introduced into the body, the cancer cells cannot function.
  • Why? Because the introduction of ozone has led to the cell producing acute oxidative stress, which is something the cancer cells cannot handle.

This set of reactions above is THE very same reason that non-cancer cells can safely handle toxic ozone doses for cancer cells.

The mechanisms by which ozone attacks cancer cells have been published in high-impact journals during the past six decades.

Ozone also has indirect methods of affecting cancer and tumour growth:

  • Secondary messengers such as 4-hydroxynonenal (4-HNE), H2O2, and lipoperoxides are distributed throughout the body.
  • These secondary molecules induce modulating nuclear factors NRF2 and regulate the Antioxidant Response Elements.
  • Modulating nuclear factor NFKβ means modulating the essential role of inflammation and immune response.

Thus, these above mechanisms improve immunity and increase radio-sensitivity in some tumours.

Megele et al., showed that a series of four patients with recurrent glioblastoma treated with intra-tumoural ozone showed increased survival of 30.5 months compared with the standard value of 11.9 months, together with the standard protocol of chemotherapy.

Many other papers, mainly in case reports or short case-control series, have suggested a combined effect of ozone with radiotherapy and chemotherapy.
The oxygenating effect of ozone can indeed increase the radio-sensitivity of some tumours and improve the survival rate of people.

The modulation of the immune system induced by ozone may enhance the anti-cancer effects of other drugs.

We must also take into account the fact that cancer cells thrive in an anaerobic environment, so as a result:

  • Adding ozone to the body increases the oxygen levels in the vicinity of cancer cells, which will adversely affect the cancer cells and potentially cause apoptosis.

In a 2022 paper by Yildirim et al., the group studied the apoptotic effect of ozone therapy on the mitochondrial activity of highly metastatic breast cancer.

The group found:

  • Ozone-treated cells demonstrated an increased rate of death.
  • Ozone-treated cells also showed decreased migration potential.
  • RT-PCR analysis showed that ozone-treated cells had higher mRNA expression levels of pro-apoptotic genes.
  • Cell cycle analysis concluded that ozone therapy for cancer treatment causes apoptotic cell death in breast tumour cells.

The Dr Otto Warburg’s theory of cancer cells fits in nicely with the use of ozone.

  • Cancer cells multiple in a low-oxygen environment.
  • So high oxygen levels will damage the cancer cells.
  • Therefore, ozone yields cytotoxic effects on cancer.

The study produced by Yildirim et al., states the team demonstrated that ozone treatment could induce an anti-cancer effect on breast cancer cell lines.

Furthermore, when the RT-PCR results were examined, it was seen that pro-apoptotic genes decreased and anti-apoptotic genes increased.

This is the KEY result of the study that supports that ozone is effective in cancer.

In summary, the evidence reported by Yildirim et al., clearly suggests that ozone has therapeutic effects on cancer cells while having little to no cytotoxicity on normal cells.


The friendly staff at BluVida Health and Wellness is committed to your health.

We care for you here at BluVida, so we provide ozone therapy as complementary therapy for cancer.

Ozone therapy is a complementary treatment alongside conventional medical treatments like chemotherapy and radiation therapy.

We want to give our patients every opportunity possible to fight their disease.

At BluVida, we believe everyone deserves to enjoy life regardless of their diagnosis. That’s why we provide this service at no cost to our clients so they can feel better while fighting their disease!

When you come in for a consultation with our doctors, they’ll be able to tell you if ozone therapy is right for you. If so, they’ll go over the benefits of this treatment in more detail and ensure that it’s safe for you to undergo while undergoing traditional treatments like chemotherapy or radiation therapy.

Our doctors, nurses, and wellness professionals will work together to determine the best course of action for your unique situation. We want to help you feel better than ever!

BluVida Health and Wellness are here for you, and we’re here for the community who have been diagnosed with cancer or are in remission.

We cater ozone to the area of Katy, Texas.

We also cater to the surrounding areas, such as:

  • Mission Bend, TX.
  • Pecan Grove, TX.
  • Richmond, TX.
  • Sugar Land, TX.
  • Stafford, TX.

Our team of experienced, compassionate professionals is dedicated to helping you get through this time with as little stress as possible.

We understand that life-changing experiences like this can be tough to deal with, which is why we want to help you with any health problems that might arise.

Reference List:

Clavo, B., Santana-Rodríguez, N., Llontop, P., Gutiérrez, D., Suárez, G., López, L., Rovira, G., Martínez-Sánchez, G., González, E., Jorge, I. J., Perera, C., Blanco, J., & Rodríguez-Esparragón, F. (2018). Ozone therapy as adjuvant for cancer treatment: Is further research warranted? Evidence-Based Complementary and Alternative Medicine, 2018, 1–11. https://doi.org/10.1155/2018/7931849 

Sweet, F., Kao, M.-S., Lee, S.-C., Hagar, W. L., & Sweet, W. E. (1980). Ozone selectively inhibits growth of human cancer cells. Science, 209(4459), 931–933. https://doi.org/10.1126/science.7403859 

BRINKMAN, R., & LAMBERTS, H. B. (1958). Ozone as a possible Radiomimetic Gas. Nature, 181(4617), 1202–1203. https://doi.org/10.1038/1811202a0 

Baeza-Noci, J., & Pinto-Bonilla, R. (2021). Systemic review: Ozone: A potential new chemotherapy. International Journal of Molecular Sciences, 22(21), 11796. https://doi.org/10.3390/ijms222111796 

Kuroda, K., Yamashita, M., Murahata, Y., Azuma, K., Osaki, T., Tsuka, T., Ito, N., Imagawa, T., & Okamoto, Y. (2018). Use of ozonated water as a new therapeutic approach to solve current concerns around antitumor treatment. Experimental and Therapeutic Medicine. https://doi.org/10.3892/etm.2018.6415 

Yıldırım, M., Erkişi, S., Yılmaz, H., Ünsal, N., İnaç, E., Tanrıver, Y., & Koçak, P. (2022). The apoptotic effect of ozone therapy on mitochondrial activity of highly metastatic breast cancer cell line MDA-MB-231 using in vitro approaches. Journal of Interventional Medicine, 5(2), 64–71. https://doi.org/10.1016/j.jimed.2022.03.004